Thromboelastography in mild, chronic liver disease: challenging conventional coagulation tests preceding liver biopsy

Tests of coagulation in liver disease.

The complex coagulation defect secondary to chronic liver disease is considered responsible for the bleeding problems that often are associated with the disease. Accordingly, clinicians order laboratory tests to assess the risk of bleeding and rely on these results to make decisions about the management of the associated coagulation disturbances. Recent data, however, indicate that the abnormal...

Comparison of conventional coagulation tests and thromboelastography for preoperatively assessing blood loss and transfusion during orthotopic liver transplantation

Objective: An effective blood loss and transfusion requirements assessment before orthotopic liver transplantation (OLT) may improve intraoperative bleeding management during OLT. Methods: Sixty-five patients were included in this retrospective, observational study. Correlations of conventional coagulation tests (CCTs) and TEG parameters with blood loss and transfusions were determined using Pe...

liver biopsy versus non-invasive tests in determining liver disease status

Utility of Modeling End-Stage Liver Disease in Children with Chronic Liver Disease

Introduction: Chronic liver diseases consist of wide spectrum disorders that may be complicated by cirrhosis and therefore need to transplantation. The pediatric end-stage liver disease (PELD) score and model of end-stage liver disease (MELD) score has been used as predictors of mortality chronic liver diseases listed for liver transplantation. The aim of this study is evaluation of relation be...

Coagulation in Liver Disease